{"id":179,"date":"2026-05-03T14:50:05","date_gmt":"2026-05-03T06:50:05","guid":{"rendered":"https:\/\/qdszxyy.com\/?p=179"},"modified":"2026-05-03T14:50:05","modified_gmt":"2026-05-03T06:50:05","slug":"%e7%99%ab%e7%97%ab%e7%81%b6%e5%88%86%e6%9e%90-sbm","status":"publish","type":"post","link":"https:\/\/qdszxyy.com\/?p=179","title":{"rendered":"\u766b\u75eb\u7076\u5206\u6790 SBM"},"content":{"rendered":"

\u75c5\u5386\u4e00<\/h2>\n

\u4e00\u3001Matlab\u2192\u2192spm\u2192cat12\u2192segment<\/p>\n

    \n
  1. T1\u56fe\u50cf\u88ab\u5f52\u4e00\u5316<\/b>\u81f3\u6a21\u677f\u7a7a\u95f4\uff0c\u5e76\u5206\u5272<\/b>\u4e3a\u7070\u8d28\uff08GM\uff09\u3001\u767d\u8d28\uff08WM\uff09\u548c\u8111\u810a\u6db2<\/li>\n
  2. \u9884\u5904\u7406\u5b8c\u6210\u540e\uff0c\u5f3a\u70c8\u5efa\u8bae\u8fdb\u884c\u8d28\u91cf\u68c0\u67e5.<\/b>\u53ef\u901a\u8fc7\u201c\u663e\u793a\u5207\u7247\u201d\u548c\u201c\u68c0\u67e5\u6837\u672c\u201d\u6a21\u5757\u5b9e\u73b0\uff0c\u8fd9\u4e24\u4e2a\u9009\u9879\u5747\u4f4d\u4e8eCAT12\u7a97\u53e3\u7684\u201c\u68c0\u67e5\u6570\u636e\u8d28\u91cf\u201d\u680f\u76ee\u4e0b\u3002<\/li>\n
  3. \u5728\u5c06GM\u56fe\u50cf\u8f93\u5165\u7edf\u8ba1\u6a21\u578b\u524d\uff0c\u9700\u5bf9\u56fe\u50cf\u6570\u636e\u8fdb\u884c\u5e73\u6ed1\u5904\u7406<\/b>\u3002\u9700\u6ce8\u610f\u7684\u662f\uff0c\u8be5\u6b65\u9aa4\u672a\u96c6\u6210\u4e8eCAT12\u5de5\u5177\u7bb1\uff0c\u800c\u662f\u901a\u8fc7\u6807\u51c6 SPM \u6a21\u5757\u201cSmooth\u201d\u5b9e\u73b0\u3002\u89c1Page12<\/li>\n<\/ol>\n

    segment\u2192\u2192Affine Regularisation\u00a0 \u00a0 \u00a0ICBM space template – East Asian brains<\/span><\/p>\n

     <\/p>\n

    \u4e8c\u3001CAT12 \u2192 Check data quality \u2192 Display slices<\/span><\/p>\n

     <\/p>\n

    \u4e09\u3001CAT12 \u2192 Statistical Analysis \u2192 Estimate TIV<\/span><\/p>\n

    XML files <-X \u2192 Select Files \u2192 [select xml-files] <\/i>\u2192 Done<\/span><\/p>\n

    —Select the xml-files in the report-folder [e.g. the \u201ccat_*.xml\u201d].<\/span><\/p>\n

    Save values \u2192 TIV only<\/i><\/span><\/p>\n

     <\/p>\n

    \u56db\u3001CAT12 \u2192 \u68c0\u67e5\u6570\u636e\u8d28\u91cf \u2192 \u68c0\u67e5\u6837\u672c \u2192 VBM \u6570\u636e\u540c\u8d28\u6027<\/span><\/p>\n

    CAT12 \u2192 Check data quality \u2192 Check sample \u2192 VBM data homogeneity<\/span><\/p>\n

     <\/p>\n

    \u4e94\u3001CAT12 \u2192 \u8868\u9762\u5de5\u5177 \u2192 \u8868\u9762\u91cd\u91c7\u6837<\/p>\n

    CAT12 \u2192 Surface Tools \u2192 Resample Surfaces<\/p>\n

    \"\"<\/p>\n

    \"\"<\/p>\n

    FWHM \u4e2d\u7684\u5e73\u6ed1\u6ee4\u6ce2\u5668\u5927\u5c0f[\u4f7f\u7528\u9ed8\u8ba4\u503c\u6216\u4fee\u6539<\/i>] <\/i><\/p>\n

    – –12-15\u6beb\u7c73\u7684\u6838\u7d20\u7c92\u5f84\u88ab\u5e7f\u6cdb\u7528\u4e8eSBM\u5206\u6790\uff0c\u5efa\u8bae\u539a\u5ea6\u6570\u636e\u521d\u59cb\u503c\u91c7\u752815\u6beb\u7c73\uff0c\u6298\u53e0\u6570\u636e\uff08\u5982\u8111\u56de\u5f62\u6210\u3001\u590d\u6742\u5ea6\uff09\u521d\u59cb\u503c\u91c7\u752820\u6beb\u7c73<\/p>\n

     <\/p>\n

    \u516d\u3001Building the Statistical Model<\/b><\/p>\n

    two-sample t-test<\/p>\n

    \u6211\u4eec\u8981\u627e\u7684\u662f\uff1a\u60a3\u8005\u7ec4 < \u5bf9\u7167\u7ec4<\/strong> \u7684\u533a\u57df\uff08\u7070\u8d28\u840e\u7f29\u533a\uff09\u3002<\/p>\n

     <\/p>\n

    \u4e03\u3001\u6a21\u578b\u4f30\u8ba1 (Model Estimation)<\/p>\n

      \n
    • \u64cd\u4f5c<\/strong>\uff1aCAT12 -> Estimate<\/code>\uff0c\u9009\u62e9\u4e0a\u4e00\u6b65\u751f\u6210\u7684 SPM.mat<\/code> \u6587\u4ef6\u3002<\/li>\n
    • \"\"<\/li>\n<\/ul>\n

       <\/p>\n

      CAT12—View models<\/p>\n

        \n
      • \u5bf9\u6bd4\u8bbe\u7f6e (Contrasts)<\/strong>\uff1a\n
          \n
        • \u8981\u5bfb\u627e\u766b\u75eb\u7076\uff08\u840e\u7f29\u533a\uff09\uff0c\u8bbe\u7f6e Contrast \u4e3a [<span style=\"color: rgb(224, 62, 45);\">1 -1]<\/span><\/code> (\u5047\u8bbe Group 1 \u662f\u60a3\u8005\uff0cGroup 2 \u662f\u5bf9\u7167)\uff0c\u5373 Patient < Control<\/strong>\u3002<\/li>\n<\/ul>\n<\/li>\n
        • \u9608\u503c\u8bbe\u5b9a<\/strong>\uff1a\n
            \n
          • P-value<\/strong>\uff1a\u901a\u5e38\u8bbe\u4e3a 0.001<\/code> (\u672a\u6821\u6b63) \u6216 0.05<\/code> (FWE \u6821\u6b63\uff0cFamily Wise Error)\u3002<\/li>\n
          • Extent Threshold (k)<\/strong>\uff1a\u8bbe\u4e3a 50<\/code> \u6216 100<\/code> \u4e2a\u4f53\u7d20\uff0c\u53bb\u9664\u566a\u70b9\u3002<\/li>\n<\/ul>\n<\/li>\n
          • <\/li>\n<\/ul>\n

            \ud83e\udde0 \u4e3a\u4ec0\u4e48\u8981\u586b -1 1<\/code>\uff1f<\/span><\/h3>\n

            \u770b\u53f3\u8fb9\u7684 Design Matrix\uff08\u8bbe\u8ba1\u77e9\u9635\uff09<\/strong> \u56fe\uff1a<\/span><\/p>\n

              \n
            • \u5de6\u8fb9\u7070\u8272\u5757<\/strong>\uff1a\u4ee3\u8868 Group 1<\/strong> (\u4f60\u8bbe\u7f6e\u7684 Patient<\/strong> \u60a3\u8005\u7ec4)\u3002<\/span><\/li>\n
            • \u53f3\u8fb9\u767d\u8272\u5757<\/strong>\uff1a\u4ee3\u8868 Group 2<\/strong> (\u4f60\u8bbe\u7f6e\u7684 Control<\/strong> \u5bf9\u7167\u7ec4)\u3002<\/span><\/li>\n<\/ul>\n

              \u4f60\u7684\u76ee\u6807\u662f\u627e \u60a3\u8005 < \u5bf9\u7167<\/strong> (\u5373\u60a3\u8005\u840e\u7f29\uff0c\u4f53\u79ef\u66f4\u5c0f) \u7684\u533a\u57df\u3002<\/span>
              \n\u6570\u5b66\u516c\u5f0f\u662f\uff1aControl - Patient > 0<\/code><\/span>
              \n\u5bf9\u5e94\u6743\u91cd\u5c31\u662f\uff1a(-1) * Patient + (1) * Control<\/code><\/span><\/p>\n

              \u6240\u4ee5\u6743\u91cd\u5411\u91cf\u662f [-1 1]<\/code><\/strong>\u3002<\/span><\/p>\n\n\n\n\n\n\n\n
              \u5982\u679c\u4f60\u60f3\u627e…<\/th>\n\u6743\u91cd\u5411\u91cf<\/th>\n\u542b\u4e49<\/th>\n<\/tr>\n<\/thead>\n
              \u60a3\u8005\u840e\u7f29\u533a<\/strong> (Patient < Control)<\/td>\n-1 1<\/code><\/strong><\/td>\n\u2705 \u8fd9\u662f\u4f60\u8981\u9009\u7684\uff01<\/strong> (\u766b\u75eb\u7076\u901a\u5e38\u662f\u840e\u7f29)<\/td>\n<\/tr>\n
              \u60a3\u8005\u589e\u751f\u533a (Patient > Control)<\/td>\n1 -1<\/code><\/td>\n\u5bfb\u627e\u7070\u8d28\u589e\u591a\/\u80bf\u80c0 (\u8f83\u5c11\u89c1)<\/td>\n<\/tr>\n
              \u4efb\u4f55\u5dee\u5f02 (\u53cc\u5411)<\/td>\n\u9700\u5b9a\u4e49\u4e24\u4e2a\u5bf9\u6bd4<\/td>\n\u540c\u65f6\u627e\u840e\u7f29\u548c\u589e\u751f<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

              \u586b\u597d\u5e76\u63d0\u4ea4\u540e\uff0c\u70b9\u51fb OK<\/code><\/strong>\u3002
              \nSPM \u4f1a\u8df3\u8f6c\u5230 Threshold<\/strong> \u8bbe\u7f6e\u754c\u9762\uff0c\u90a3\u65f6\u8bb0\u5f97\u6309\u6211\u4eec\u4e4b\u524d\u8ba8\u8bba\u7684\uff1a<\/p>\n

                \n
              • P-value adjustment<\/strong>: none<\/code><\/li>\n
              • P-value<\/strong>: 0.001<\/code><\/li>\n
              • Extent threshold<\/strong>: 50<\/code><\/li>\n
              • \u70b9\u51fb Apply<\/code><\/strong> \u770b\u7ed3\u679c\uff01<\/li>\n<\/ul>\n

                \"\"<\/p>\n

                \"\"<\/p>\n

                 <\/p>\n

                <\/div>\n

                <\/path><\/svg><\/i> \"Loading\"<\/p>\n

                <\/div>\n","protected":false},"excerpt":{"rendered":"

                \u75c5\u5386\u4e00 \u4e00\u3001Matlab\u2192\u2192spm\u2192cat12\u2192segment T1\u56fe\u50cf\u88ab\u5f52\u4e00\u5316\u81f3\u6a21\u677f\u7a7a\u95f4\uff0c\u5e76\u5206\u5272\u4e3a\u7070\u8d28\uff08GM […]<\/p>\n

                <\/div>\n

                <\/path><\/svg><\/i> \"Loading\"<\/p>\n

                <\/div>\n","protected":false},"author":1,"featured_media":193,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,16],"tags":[],"class_list":["post-179","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","category-epilepsy"],"_links":{"self":[{"href":"https:\/\/qdszxyy.com\/index.php?rest_route=\/wp\/v2\/posts\/179","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/qdszxyy.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/qdszxyy.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/qdszxyy.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/qdszxyy.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=179"}],"version-history":[{"count":7,"href":"https:\/\/qdszxyy.com\/index.php?rest_route=\/wp\/v2\/posts\/179\/revisions"}],"predecessor-version":[{"id":194,"href":"https:\/\/qdszxyy.com\/index.php?rest_route=\/wp\/v2\/posts\/179\/revisions\/194"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/qdszxyy.com\/index.php?rest_route=\/wp\/v2\/media\/193"}],"wp:attachment":[{"href":"https:\/\/qdszxyy.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=179"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/qdszxyy.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=179"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/qdszxyy.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=179"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}